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1

Isolierung, Chemie und Biochemie von Ptaquilosid, einem Carcinogen des Adlerfarns

Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi

Journal:

Angewandte Chemie

Année:

1998

Langue:

german

Fichier:

PDF, 1.22 MB

german, 1998

2

Isolation, Chemistry, and Biochemistry of Ptaquiloside, a Bracken Carcinogen

Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi

Journal:

Angewandte Chemie International Edition

Année:

1998

Langue:

english

Fichier:

PDF, 1.22 MB

english, 1998

3

(10R̃, 11R̃)-(+)-squalene-10, 11-epoxide: Isolation from Laurencia okamurai and the asymmetric synthesis

Hideo Kigoshi, Makoto Ojika, Yoshikazu Shizuri, Haruki Niwa, Kiyoyuki Yamada

Journal:

Tetrahedron Letters

Année:

1982

Langue:

english

Fichier:

PDF, 125 KB

english, 1982

4

Synthetic Studies on Aplyronine A, a Potent Antitumor Substance of Marine Origin: Stereocontrolled Synthesis of the C21–C34 Segment

Hideo Kigoshi, Makoto Ojika, Kiyotake Suenaga, Tsuyoshi Mutou, Junko Hirano, Akira Sakakura, Takeshi Ogawa, Masanori Nisiwaki, Kiyoyuki Yamada

Journal:

Tetrahedron Letters

Année:

1994

Langue:

english

Fichier:

PDF, 294 KB

english, 1994

5

Synthesis of dolastatin G and nordolastatin G, cytotoxic 35-membered cyclodepsipeptides of marine origin

Tsuyoshi Mutou, Takashi Kondo, Takunobu Shibata, Makoto Ojika, Hideo Kigoshi, Kiyoyuki Yamada

Journal:

Tetrahedron Letters

Année:

1996

Langue:

english

Fichier:

PDF, 218 KB

english, 1996

6

Aplyronine A, a potent antitumor macrolide of marine origin, and the congeners aplyronines B and C: isolation, structures, and bioactivities

Makoto Ojika, Hideo Kigoshi, Yoshifumi Yoshida, Takeshi Ishigaki, Masanori Nisiwaki, Itaru Tsukada, Masayuki Arakawa, Hisao Ekimoto, Kiyoyuki Yamada

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 677 KB

english, 2007

7

Further studies on aplyronine A, an antitumor substance isolated from the sea hare Aplysia kurodai

Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, Kiyoyuki Yamada

Journal:

Tetrahedron Letters

Année:

1993

Langue:

english

Fichier:

PDF, 320 KB

english, 1993

8

Studies on the stereochemistry of aplyronine A: Determination of the stereochemistry of the C21C34 fragment

Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, Masanori Nisiwaki, Itaru Tsukada, Kazuhiro Mizuta, Kiyoyuki Yamada

Journal:

Tetrahedron Letters

Année:

1993

Langue:

english

Fichier:

PDF, 221 KB

english, 1993

9

Isolation of (10R,11R)-(+)-squalene-10,11-epoxide from the red alga laurencia okamurai and its enantioselective synthesis

Hideo Kigoshi, Makoto Ojika, Yoshikazu Shizuri, Haruki Niwa, Kiyoyuki Yamada

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 362 KB

english, 1986

10

Aplyronines D–H from the sea hare Aplysia kurodai: isolation, structures, and cytotoxicity

Makoto Ojika, Hideo Kigoshi, Kiyotake Suenaga, Yoshifumi Imamura, Kohji Yoshikawa, Takeshi Ishigaki, Akira Sakakura, Tsuyoshi Mutou, Kiyoyuki Yamada

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 335 KB

english, 2012

11

Reversed Circadian Blood Pressure Rhythm Independently Predicts Endstage Renal Failure in Non–Insulin-Dependent Diabetes Mellitus Subjects

Shigeru Nakano, Mari Ogihara, Chinami Tamura, Mitsutaka Kitazawa, Makoto Nishizawa, Toshikazu Kigoshi, Kenzo Uchida

Journal:

Journal of Diabetes and its Complications

Année:

1999

Langue:

english

Fichier:

PDF, 196 KB

english, 1999

12

Mitochondrial DNA Mutations Are Associated with Both Decreased Insulin Secretion and Advanced Microvascular Complications in Japanese Diabetic Subjects

Masataka Fukuda, Shigeru Nakano, Noriko Imaizumi, Mitsutaka Kitazawa, Makoto Nishizawa, Toshikazu Kigoshi, Kenzo Uchida

Journal:

Journal of Diabetes and its Complications

Année:

1999

Langue:

english

Fichier:

PDF, 138 KB

english, 1999

13

Aplyronine A, a Potent Antitumor Substance of Marine Origin, Aplyronines B and C, and Artificial Analogues: Total Synthesis and Structure−Cytotoxicity Relationships

Kigoshi, Hideo, Suenaga, Kiyotake, Mutou, Tsuyoshi, Ishigaki, Takeshi, Atsumi, Toshiyuki, Ishiwata, Hiroyuki, Sakakura, Akira, Ogawa, Takeshi, Ojika, Makoto, Yamada, Kiyoyuki

Journal:

Journal of Organic Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1996

14

Action of β-Carotene as an Antioxidant against Lipid Peroxidation

Hideyasu Tsuchihashi, Makoto Kigoshi, Misato Iwatsuki, Etsuo Niki

Journal:

Archives of Biochemistry and Biophysics

Année:

1995

Langue:

english

Fichier:

PDF, 197 KB

english, 1995

15

Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells

Atsushi Nakagawa, Hanae Satake, Hajime Nakabayashi, Makoto Nishizawa, Keisuke Furuya, Shigeru Nakano, Toshikazu Kigoshi, Kohzo Nakayama, Kenzo Uchida

Journal:

Autonomic Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 933 KB

english, 2004

16

Testosterone inhibits tumor necrosis factor-α-induced vascular cell adhesion molecule-1 expression in human aortic endothelial cells

Haruhiko Hatakeyama, Makoto Nishizawa, Atsushi Nakagawa, Shigeru Nakano, Toshikazu Kigoshi, Kenzo Uchida

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 185 KB

english, 2002

17

Total Synthesis of Aplyronine A, a Potent Antitumor Substance of Marine Origin

Kigoshi, Hideo, Ojika, Makoto, Ishigaki, Takeshi, Suenaga, Kiyotake, Mutou, Tsuyoshi, Sakakura, Akira, Ogawa, Takeshi, Yamada, Kiyoyuki

Journal:

Journal of the American Chemical Society

Année:

1994

Langue:

english

Fichier:

PDF, 264 KB

english, 1994

18

Ptaquiloside, the major toxin of bracken, and related terpene glycosides: chemistry, biology and ecology

Yamada, Kiyoyuki, Ojika, Makoto, Kigoshi, Hideo

Journal:

Natural Product Reports

Année:

2007

Langue:

english

Fichier:

PDF, 477 KB

english, 2007

19

Studies on Pteridium aquilinum var. latiusculum, IV. Isolation of Three p-Hydroxystyrene Glycosides and an Efficient Method for the Isolation of Ptaquiloside, an Unstable Bracken Carcinogen

Ojika, Makoto, Kigoshi, Hideo, Kuyama, Hiroki, Niua, Haruki, Yamada, Kiyoyuki

Journal:

Journal of Natural Products

Année:

1985

Langue:

english

Fichier:

PDF, 267 KB

english, 1985

20

Separation of carcinogenic fraction of bracken fern

Hirono, Iwao, Yamada, Kiyoyuki, Niwa, Haruki, Shizuri, Yoshikazu, Ojika, Makoto, Hosaka, Shigetoshi, Yamaji, Taketo, Wakamatsu, Kazumasa, Kigoshi, Hideo, Niiyama, Kenji

Journal:

Année:

1984

Langue:

english

Fichier:

PDF, 465 KB

english, 1984

21

DNA damage by ptaquiloside, a potent bracken carcinogen: detection of selective strand breaks and identification of DNA cleavage products

Kushida, Tatsushi, Uesugi, Motonari, Sugiura, Yukio, Kigoshi, Hideo, Tanaka, Hideyuki, Hirokawa, Junichi, Ojika, Makoto, Yamada, Kiyoyuki

Journal:

Journal of the American Chemical Society

Année:

1994

Langue:

english

Fichier:

PDF, 2.71 MB

english, 1994

22

Absolute Stereochemistry of Aplyronine A, a Potent Antitumor Substance of Marine Origin

Ojika, Makoto, Kigoshi, Hideo, Ishigaki, Takeshi, Tsukada, Itaru, Tsuboi, Takaya, Ogawa, Takeshi, Yamada, Kiyoyuki

Journal:

Journal of the American Chemical Society

Année:

1994

Langue:

english

Fichier:

PDF, 250 KB

english, 1994

23

Quantitative Analysis of Saponins in a Tea-Leaf Extract and Their Antihypercholesterolemic Activity

MATSUI, Yoko, KOBAYASHI, Keiko, MASUDA, Hideki, KIGOSHI, Hideo, AKAO, Makoto, SAKURAI, Hidetoshi, KUMAGAI, Hitomi

Journal:

Bioscience Biotechnology and Biochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 191 KB

english, 2009

24

Insulin Resistant State in Type 2 Diabetes Is Related to Advanced Autonomic Neuropathy

Nakano, Shigeru, Kitazawa, Mitsutaka, Ito, Tomohiko, Hatakeyama, Haruhiko, Nishizawa, Makoto, Nakagawa, Atsushi, Kigoshi, Toshikazu, Uchida, Kenzo

Journal:

Clinical and Experimental Hypertension

Année:

2003

Langue:

english

Fichier:

PDF, 211 KB

english, 2003

25

A New Bromo Diterpene, epi -Aplysin-20, and ent -Isoconcinndiol from the Marine Mollusc Aplysia kurodai

Ojika, Makoto, Kigoshi, Hideo, Yoshikawa, Kohji, Nakayama, Yoshisuke, Yamada, Kiyoyuki

Journal:

Bulletin of the Chemical Society of Japan

Année:

1992

Fichier:

PDF, 586 KB

1992

26

Oxidation of Lipids Induced by Dioctadecyl Hyponitrite and Di- t -butyl Hyponitrite in Organic Solution and in Aqueous Dispersions. Effects of Reaction Medium and Size of Radicals on Efficiency of Chain Initiation

Kigoshi, Makoto, Sato, Keizo, Niki, Etsuo

Journal:

Bulletin of the Chemical Society of Japan

Année:

1993

Fichier:

PDF, 869 KB

1993

27

A Case of Familial Hypokalemic Periodic Paralysis Associated with Cardiac Arrest

KITAZAWA, Mitsutaka, ISHII, Takashi, HOTTA, Fumitaka, NISHIZAWA, Makoto, NAKANO, Shigeru, KIGOSHI, Toshikazu, UCHIDA, Kenzo

Journal:

Folia Endocrinologica Japonica

Année:

1997

Fichier:

PDF, 672 KB

1997

28

Potentiating Effects of Calcium Chelators on Basal and Stimulated Aldosterone Production by Bovine Adrenal Glomerulosa Cells In Vitro.

KIGOSHI, TOSHIKAZU, OKAMOTO, HIROSHI, ISHII, TAKASHI, ITO, TOMOHIKO, HOTTA, FUMITAKE, KITAZAWA, MITSUTAKA, NISHIZAWA, MAKOTO, NAKANO, SHIGERU, MORIMOTO, SHINPEI, UCHIDA, KENZO

Journal:

Endocrine Journal

Année:

1997

Langue:

english

Fichier:

PDF, 717 KB

english, 1997

29

Mitochondrial DNA Point Mutation at Nucleotide Pair 3316 in a Japanese Family with Heterogeneous Phenotypes of Diabetes.

NAKANO, SHIGERU, FUKUDA, MASATAKA, HOTTA, FUMITAKE, ITO, TOMOHIKO, ISHII, TAKASHI, KITAZAWA, MITSUTAKA, NISHIZAWA, MAKOTO, KIGOSHI, TOSHIKAZU, KAKINUMA, HIROAKI, TAKAHASHI, HIROAKI, UCHIDA, KENZO

Journal:

Endocrine Journal

Année:

1998

Langue:

english

Fichier:

PDF, 1.53 MB

english, 1998

30

Reproduction of Progressive Retinal Degeneration(Bright Blindness) in Sheep by Administration of Ptaquiloside Contained in Bracken.

HIRONO, Iwao, ITO, Mitsuya, YAGYU, Shigeru, HAGA, Masanobu, WAKAMATSU, Kazumasa, KISHIKAWA, Teruaki, NISHIKAWA, Osamu, YAMADA, Kiyoyuki, OJIKA, Makoto, KIGOSHI, Hideo

Journal:

Journal of Veterinary Medical Science

Année:

1993

Fichier:

PDF, 1.12 MB

1993

31

Rapidly Progressive Glomerulonephritis Concomitant with Diabetic Nephropathy.

KITAZAWA, Mitsutaka, TOMOSUGI, Naohisa, ISHII, Takashi, HOTTA, Fumitake, NISHIZAWA, Makoto, ITOU, Tomohiko, NAKANO, Shigeru, KIGOSHI, Toshikazu, ISHIKAWA, Isao, UCHIDA, Kenzo

Journal:

Internal Medicine

Année:

1997

Langue:

english

Fichier:

PDF, 1.90 MB

english, 1997

32

Cytotoxic substances from two species of Japanese sea hares: chemistry and bioactivity

YAMADA, Kiyoyuki, OJIKA, Makoto, KIGOSHI, Hideo, SUENAGA, Kiyotake

Journal:

Proceedings of the Japan Academy Series B Physical and Biological Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2010

33

Relationship between Impaired Aldosterone Response to Adrenocorticotropic Hormone and Prevalence of Hemodialysis in Type 2 Diabetic Patients without Azotemia

KIGOSHI, Toshikazu, UEHARA, Keigo, FURUYA, Keisuke, KONISHI, Kazunori, FUKUDA, Masataka, ITO, Tomohiko, NISHIZAWA, Makoto, NAKAGAWA, Atsushi, NAKANO, Shigeru, UCHIDA, Kenzo

Journal:

Hypertension Research

Année:

2005

Langue:

english

Fichier:

PDF, 113 KB

english, 2005

34

Ambulatory Blood Pressure Level Rather than Dipper/Nondipper Status Predicts Vascular Events in Type 2 Diabetic Subjects

NAKANO, Shigeru, ITO, Tomohiko, FURUYA, Keisuke, TSUDA, Shin-ichi, KONISHI, Kazunori, NISHIZAWA, Makoto, NAKAGAWA, Atsushi, KIGOSHI, Toshikazu, UCHIDA, Kenzo

Journal:

Hypertension Research

Année:

2004

Langue:

english

Fichier:

PDF, 272 KB

english, 2004